Introduction Lipids are a heterogeneous group of water-insoluble organic molecules that can be extracted from tissues by non-polar solvents. They are the major source of energy for the body. Dietary fat Composition More than 95% are triglycerides, the other are -Cholesteryl esters, phospholipids, and unesterified fatty acids. Dietary sources of Lipids a) Animal Sources Dairy […]
Digestion of lipids Read More »
Enzyme Pathway Effect of Substrate Concentration Allosteric Modification/ Feedback Inhibition Induction/Repression Clinical Significance Hexokinase Glycolysis Feedback inhibition by Glucose-6-P – Deficiency causes Hemolytic anemia. Glucokinase Glycolysis Stimulated by a high carbohydrate diet Activity decreases during fasting – Induced by Insulin Repressed by Glucagon Activity low in Diabetes Mellitus Phosphofructokinase-1 Glycolysis Stimulated by a high
Summary- Regulation of Major Pathways Of Carbohydrate metabolism Read More »
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Quiz- Vitamins and Minerals Read More »
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Quiz-Chemistry and metabolism of Carbohydrates and Lipids Read More »
Enzyme Pathway Effect of substrate concentration Allosteric Modification/Feedback Inhibition Induction/ Repression Clinical Significance Acetyl CoA Carboxylase Fatty acid synthesis Activity increases during well-fed state Activity decreases during fasting Activator- Citrate, ATP Acetyl CoA Insulin-by causing de-phosphorylation by stimulating protein phosphatase Inhibitors- Long-chain fatty acids, Epinephrine, Glucagon- via changes in phosphorylation state through c AMP mediated phosphorylation cascade Induced
Regulatory Mechanisms- Lipid Metabolism (Summary Chart) Read More »
A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes
Hypoglycemia Due To Biotin deficiency Read More »
Case details A 44-year-old man who had lost his job because of absenteeism presented to his physician complaining of loss of appetite, fatigue, muscle weakness, and emotional depression. The physical examination revealed a somewhat enlarged liver that was firm and nodular, and there was a hint of jaundice in the sclerae and a hint of
Case study-Folic Acid Deficiency Read More »
