Tumor markers Tumor markers are hormones, enzymes, peptides or proteins abnormally synthesized and released by the cancer cells, or are produced by the host cells in response to cancerous growth. Tumor markers may be present in the body fluids, blood, cell membranes or in the cytoplasm of the cell. Clinical significance of tumor markers Tumor […]
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Methotrexate Methotrexate is an antimetabolite. A broad definition of antimetabolites would include compounds with structural similarity to precursors of purines or pyrimidines or compounds that interfere with purine or pyrimidine synthesis. Antimetabolites can cause DNA damage indirectly, through misincorporation into DNA, abnormal timing or progression through DNA synthesis, or altered function of pyrimidine and purine
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