Multiple-choice questions

NBME-Style Case-Based Questions on the regulation of glycolysis with explanations

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Question 1: A 25-year-old man runs a marathon. After 20 miles, his muscle cells are relying heavily on glycolysis for energy production. Which of the following changes is most likely increasing the rate of glycolysis in his muscles? A. Accumulation of alanine B. Decreased availability of glucose C. Decreased oxygen levels D. Increased AMP concentration […]

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Starvation induced metabolic alterations

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 A 23 –year- old female was brought for consultation by her mother, who was troubled by her daughter’s continuous fatigue, dizziness, and loss of weight. The patient was 6 feet 2 inches tall and weighed 100 pounds. Further questioning revealed that the young woman had been virtually fasting for four months, hoping to obtain a

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Question the week-2 (Answer)

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A 65-year-old man with a history of type 2 diabetes mellitus is complaining of blurred vision and numbness in his toes. Laboratory results are significant for an increased BUN and creatinine, indicative of renal failure, and high HbA1c, indicative of chronic persistent hyperglycemia. Of the several proposed mechanisms, one mechanism responsible for hyperglycemia-induced complications in

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Impaired TCA cycle enzyme activity in angular stomatitis

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A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the

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Hypoglycemia Due To Biotin deficiency

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A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes

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Clinical significance of SGLT-2

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A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing

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Answer to the Question of the week -1

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A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency, given the patient’s diet and symptoms. Which

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Carbohydrate metabolism- Problem based MCQs

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1) A 30-year-old man has been fasting for religious reasons for several days.  His brain has reduced its need for glucose by using which of the following substances as an alternative source of energy? A.Fatty acids B.Beta-hydroxybutyrate C.Glycerol D.Beta carotene E. Alanine 2) A 7-year-old girl is brought to the emergency department by her parents

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Metabolism of Glycogen, Glycogen storage diseases and Diabetes mellitus- Solved MCQs

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Q.1- Which of the following is an important glycogen storage site? A) Adipose tissue B) Cardiac muscle C) Spleen D) Kidney E) Liver. Q.2- Which of the following is an active form of glucose to initiate the process of glycogenesis? A) Adenosyl Glucose B) UDP glucose C) AMP Glucose D) Glucose-6-Phosphate E) Glucose-1-P Q.3- Choose

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