1) A 24-year-old woman presents with diarrhea, dysphagia, jaundice, and white transverse lines on the fingernails (Mee’s lines). The patient is diagnosed with Arsenic poisoning, which inhibits which of the following enzymes? a) Citrate synthase b) Isocitrate dehydrogenase c) α-Keto glutarate dehydrogenase complex d) Succinate dehydrogenase e) Malate dehydrogenase 2) A biochemistry graduate student isolated […]
TCA Cycle- Multiple-choice questions Read More »
1) Glucose breakdown in certain mammalian and bacterial cells can occur by mechanisms other than classic glycolysis. In most of these, glucose 6-phosphate is oxidized to 6- 6-phosphogluconate, which is then further metabolized by: a) an aldolase-type split to form glyceric acid and glyceraldehyde 3-phosphate. b) an aldolase-type split to form glycolic acid and erythrose
Multiple-choice questions- Pentose phosphate pathway Read More »
1) A 4-month-old boy is being evaluated for seizures, psychomotor retardation, and hypotonia. Workup reveals elevated serum levels of lactate, alanine, pyruvate, and keto acids. Based on the clinical presentation, pyruvate carboxylase activity is measured using fibroblasts from a skin biopsy and is found to be markedly decreased. This enzyme is normally used to directly
Gluconeogenesis- Multiple-choice questions Read More »
1) Which of these enzyme reactions is not irreversible in glycolysis? a) Hexokinase b) Glucokinase c) 3-phosphoglycerate kinase d) Phosphofructokinase-1 e) Pyruvate kinase 2) Which of the following statements is not true about aerobic glycolysis? a) The rate-limiting enzyme is phosphofructokinase-1 which converts fructose-6- phosphate to fructose-1,6-bisphosphate b) The pathway is activated allosterically by fructose-2,6-bisphosphate
Carbohydrate metabolism-Practice questions Read More »
1). A patient has chronic obstructive pulmonary disease, and enough oxygen is not reaching her tissues. All of the following are expected except- a) The electron transport chain would be inhibited b) Glycolysis would be activated by a low ATP/ADP ratio c) More than normal amounts of ATP would be synthesized. d) Concentrations of NADH and
Glycolysis- Multiple-choice questions (set-1) Read More »
