Metabolism of Carbohydrates

PDH complex and the TCA cycle- NBME style questions set-1

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1. A 24-year-old woman presents with diarrhea, dysphagia, jaundice, and white transverse lines on her fingernails (Mee’s lines). She is diagnosed with arsenic poisoning. Arsenic poisoning inhibits which of the following enzymes? A. Citrate synthase B. Isocitrate dehydrogenase C. Malate dehydrogenase D. Succinate dehydrogenase E. α-Keto glutarate dehydrogenase complex Correct answer: E. α-Keto glutarate dehydrogenase […]

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Glycolysis Review- NBME style questions with complete explanations

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Q.1 Identify the Phosphoester that is predominantly encountered in erythrocytes and plays a vital role in modulating the oxygen-binding affinity of hemoglobin: A. 1,3-Bisphosphoglycerate B. 2,3-Bisphosphoglycerate C. Fructose 1,6-bisphosphate D. Fructose 6-phosphate E. Glucose 6-phosphate The correct answer is B. 2,3-Bisphosphoglycerate (2,3-BPG): 2,3-Bisphosphoglycerate is a negatively charged molecule found in high concentrations within erythrocytes. 2,3-BPG

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NBME-Style Case-Based Questions on the regulation of glycolysis with explanations

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Question 1: A 25-year-old man runs a marathon. After 20 miles, his muscle cells are relying heavily on glycolysis for energy production. Which of the following changes is most likely increasing the rate of glycolysis in his muscles? A. Accumulation of alanine B. Decreased availability of glucose C. Decreased oxygen levels D. Increased AMP concentration

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Summary of Regulation of Glycolysis

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Glycolysis is the metabolic pathway that converts glucose into pyruvate, generating ATP and NADH in the process. It occurs in the cytoplasm of cells and is essential for energy production. Glycolysis is regulated at multiple levels to match energy demand with supply. Modes of Glycolysis Regulation Substrate Concentration The availability of glucose directly influences the

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A Summary Of Glycolysis

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🎧 Episode Summary: Welcome to Biochem Bytes, your go-to podcast for mastering core biochemistry topics in minutes. In today’s episode, we’re breaking down glycolysis—the central pathway of glucose metabolism. Glycolysis Simplified: Glycolysis is a 10-step metabolic pathway that occurs in the cytoplasm of all cells. It converts one molecule of glucose (a 6-carbon sugar) into

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Carbohydrate Metabolism – A Quick Revision with Multiple Choice Questions Covering All Pathways

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Revise the essential concepts of carbohydrate metabolism with this comprehensive set of multiple-choice questions spanning all major pathways—glycolysis, gluconeogenesis, TCA cycle, glycogen metabolism, and the pentose phosphate pathway. Ideal for USMLE prep and biochemistry exams, this resource offers rapid revision with clear explanations for each answer.

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Starvation induced metabolic alterations

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 A 23 –year- old female was brought for consultation by her mother, who was troubled by her daughter’s continuous fatigue, dizziness, and loss of weight. The patient was 6 feet 2 inches tall and weighed 100 pounds. Further questioning revealed that the young woman had been virtually fasting for four months, hoping to obtain a

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Question the week-2 (Answer)

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A 65-year-old man with a history of type 2 diabetes mellitus is complaining of blurred vision and numbness in his toes. Laboratory results are significant for an increased BUN and creatinine, indicative of renal failure, and high HbA1c, indicative of chronic persistent hyperglycemia. Of the several proposed mechanisms, one mechanism responsible for hyperglycemia-induced complications in

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