Metabolism of Carbohydrates

Impaired TCA cycle enzyme activity in angular stomatitis

Learning resources, Library, Metabolism of Carbohydrates, Multiple-choice questions, USMLE styled question bank /

A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the […]

Impaired TCA cycle enzyme activity in angular stomatitis Read More »

Summary- Regulation of Major Pathways Of Carbohydrate metabolism

Quick Revision Series, Energy metabolism, Learning resources, Library, Metabolism of Carbohydrates, Quick revisions, Quick revisions /

Enzyme Pathway Effect of Substrate Concentration Allosteric Modification/ Feedback Inhibition Induction/Repression Clinical Significance Hexokinase Glycolysis Feedback inhibition by Glucose-6-P – Deficiency causes Hemolytic anemia. Glucokinase Glycolysis Stimulated by a high carbohydrate diet   Activity decreases during fasting – Induced by Insulin Repressed by Glucagon Activity low in Diabetes Mellitus Phosphofructokinase-1 Glycolysis Stimulated by a high

Summary- Regulation of Major Pathways Of Carbohydrate metabolism Read More »

Hypoglycemia Due To Biotin deficiency

Energy metabolism, Metabolism of Carbohydrates, Multiple-choice questions, Multiple-Choice questions, Multiple-Choice questions, Multiple-choice questions, Practice questions, USMLE Style questions, USMLE styled question bank, Vitamins, Vitamins and Minerals /

A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes

Hypoglycemia Due To Biotin deficiency Read More »

Clinical significance of SGLT-2

Case based multiple choice questions, Metabolism of Carbohydrates, Multiple-choice questions, Practice questions, USMLE styled question bank /

A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing

Clinical significance of SGLT-2 Read More »

Answer to the Question of the week -1

Image Challenge, Metabolism of Carbohydrates, Multiple-choice questions, Multiple-choice questions, Practice questions /

A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency, given the patient’s diet and symptoms. Which

Answer to the Question of the week -1 Read More »

Carbohydrate metabolism- Problem based MCQs

Metabolism of Carbohydrates, Multiple choice questions, Multiple-choice questions /

1) A 30-year-old man has been fasting for religious reasons for several days.  His brain has reduced its need for glucose by using which of the following substances as an alternative source of energy? A.Fatty acids B.Beta-hydroxybutyrate C.Glycerol D.Beta carotene E. Alanine 2) A 7-year-old girl is brought to the emergency department by her parents

Carbohydrate metabolism- Problem based MCQs Read More »

Metabolism of Glycogen, Glycogen storage diseases and Diabetes mellitus- Solved MCQs

Learning resources, Library, Metabolism of Carbohydrates, Multiple choice questions, Multiple-choice questions /

Q.1- Which of the following is an important glycogen storage site? A) Adipose tissue B) Cardiac muscle C) Spleen D) Kidney E) Liver. Q.2- Which of the following is an active form of glucose to initiate the process of glycogenesis? A) Adenosyl Glucose B) UDP glucose C) AMP Glucose D) Glucose-6-Phosphate E) Glucose-1-P Q.3- Choose

Metabolism of Glycogen, Glycogen storage diseases and Diabetes mellitus- Solved MCQs Read More »

TCA Cycle- Multiple-choice questions

Energy metabolism, Library, Metabolism of Carbohydrates, Multiple choice questions, Multiple-Choice questions, Multiple-choice questions, Question Bank, Question Bank /

1) A 24-year-old woman presents with diarrhea, dysphagia, jaundice, and white transverse lines on the fingernails (Mee’s lines). The patient is diagnosed with Arsenic poisoning, which inhibits which of the following enzymes? a) Citrate synthase b) Isocitrate dehydrogenase c) α-Keto glutarate dehydrogenase complex d) Succinate dehydrogenase e) Malate dehydrogenase 2) A biochemistry graduate student isolated

TCA Cycle- Multiple-choice questions Read More »

Multiple-choice questions- Pentose phosphate pathway

Energy metabolism, Learning resources, Library, Metabolism of Carbohydrates, Multiple choice questions, Multiple-choice questions, Multiple-Choice questions, Question Bank, Question Bank, USMLE Content /

1) Glucose breakdown in certain mammalian and bacterial cells can occur by mechanisms other than classic glycolysis. In most of these, glucose 6-phosphate is oxidized to 6- 6-phosphogluconate, which is then further metabolized by: a) an aldolase-type split to form glyceric acid and glyceraldehyde 3-phosphate. b) an aldolase-type split to form glycolic acid and erythrose

Multiple-choice questions- Pentose phosphate pathway Read More »

Gluconeogenesis- Multiple-choice questions

Energy metabolism, Learning resources, Library, Metabolism of Carbohydrates, Multiple choice questions, Multiple-Choice questions, Multiple-choice questions, Question Bank, Question Bank, USMLE Style questions, USMLE styled question bank /

1)  A 4-month-old boy is being evaluated for seizures, psychomotor retardation, and hypotonia. Workup reveals elevated serum levels of lactate, alanine, pyruvate, and keto acids. Based on the clinical presentation, pyruvate carboxylase activity is measured using fibroblasts from a skin biopsy and is found to be markedly decreased. This enzyme is normally used to directly

Gluconeogenesis- Multiple-choice questions Read More »

×