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Impaired TCA cycle enzyme activity in angular stomatitis

Learning resources, Library, Metabolism of Carbohydrates, Multiple-choice questions, USMLE styled question bank /

A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the […]

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Digestion of lipids

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Introduction Lipids are a heterogeneous group of water-insoluble organic molecules that can be extracted from tissues by non-polar solvents. They are the major source of energy for the body. Dietary fat Composition More than 95% are triglycerides, the other are -Cholesteryl esters, phospholipids, and unesterified fatty acids. Dietary sources of Lipids a) Animal Sources Dairy

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Summary- Regulation of Major Pathways Of Carbohydrate metabolism

Quick Revision Series, Energy metabolism, Learning resources, Library, Metabolism of Carbohydrates, Quick revisions, Quick revisions /

Enzyme Pathway Effect of Substrate Concentration Allosteric Modification/ Feedback Inhibition Induction/Repression Clinical Significance Hexokinase Glycolysis Feedback inhibition by Glucose-6-P – Deficiency causes Hemolytic anemia. Glucokinase Glycolysis Stimulated by a high carbohydrate diet   Activity decreases during fasting – Induced by Insulin Repressed by Glucagon Activity low in Diabetes Mellitus Phosphofructokinase-1 Glycolysis Stimulated by a high

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Hypoglycemia Due To Biotin deficiency

Energy metabolism, Metabolism of Carbohydrates, Multiple-Choice questions, Multiple-choice questions, Multiple-choice questions, Multiple-Choice questions, Practice questions, USMLE Style questions, USMLE styled question bank, Vitamins, Vitamins and Minerals /

A 32-year-old bodybuilder has decided to go on a diet consisting of egg whites to ensure only proteins for muscle growth. After a few weeks, he experiences decreased energy and is found to be hypoglycemic. A nutritionist tells the patient that he most likely has a deficiency of vitamin Biotin. Which of the following enzymes

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Case study- Scurvy (vitamin C deficiency)

Case based discussions, Case studies, Case studies, Vitamins /

Case Details A  4 -year-old boy was brought for consultation for hematuria, edema of lower extremities, and as swollen right leg. He was the 12th born in a poor family, where one previous child died from malnutrition and dehydration in the period of infancy.  The child was fed only with cow’s milk and biscuits. From

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