1) Glucose breakdown in certain mammalian and bacterial cells can occur by mechanisms other than classic glycolysis. In most of these, glucose 6-phosphate is oxidized to 6- 6-phosphogluconate, which is then further metabolized by: a) an aldolase-type split to form glyceric acid and glyceraldehyde 3-phosphate. b) an aldolase-type split to form glycolic acid and erythrose […]
Multiple-choice questions- Pentose phosphate pathway Read More »
1) A 4-month-old boy is being evaluated for seizures, psychomotor retardation, and hypotonia. Workup reveals elevated serum levels of lactate, alanine, pyruvate, and keto acids. Based on the clinical presentation, pyruvate carboxylase activity is measured using fibroblasts from a skin biopsy and is found to be markedly decreased. This enzyme is normally used to directly
Gluconeogenesis- Multiple-choice questions Read More »
1) Which of these enzyme reactions is not irreversible in glycolysis? a) Hexokinase b) Glucokinase c) 3-phosphoglycerate kinase d) Phosphofructokinase-1 e) Pyruvate kinase 2) Which of the following statements is not true about aerobic glycolysis? a) The rate-limiting enzyme is phosphofructokinase-1 which converts fructose-6- phosphate to fructose-1,6-bisphosphate b) The pathway is activated allosterically by fructose-2,6-bisphosphate
Carbohydrate metabolism-Practice questions Read More »
1). A patient has chronic obstructive pulmonary disease, and enough oxygen is not reaching her tissues. All of the following are expected except- a) The electron transport chain would be inhibited b) Glycolysis would be activated by a low ATP/ADP ratio c) More than normal amounts of ATP would be synthesized. d) Concentrations of NADH and
Glycolysis- Multiple-choice questions (set-1) Read More »
Q.1- Which of the following is a common compound shared by the TCA and Urea cycles? a) α- Ketoglutarate b) Succinyl CoA c) Oxaloacetate d) Fumarate Q.2-Which of the following is a common nitrogen acceptor for all reactions involving transaminases? a) α- Ketoglutarate b) Pyruvate c) Oxaloacetate d) Acetoacetate Q.3- In a 55- year-old man
Amino Acid Metabolism-Multiple-choice questions (set-2) Read More »
Q.1- A 12 -year-old boy develops convulsions. After running an Electroencephalogram(EEG), a neurologist determines that the child has epilepsy. He is started on benzodiazepine, which promotes the activity of GABA. GABA is derived from Glutamate by which of the following reactions? a) Transamination b) Decarboxylation c) Deamination d) Hydroxylation e) Dehydrogenation Q.2- A couple of
Amino acid metabolism-Multiple-choice questions (set-1) Read More »
Q.1- Which statement best describes the ‘semi-conservative replication’ of DNA? A) In each replication cycle, only one of the two DNA strands is replicated B) In each replication cycle, one of the parental strands is conserved C) In each replication cycle, the daughter cells acquire either the parental stands or new stands D) Only half
Molecular Biology-Multiple-choice questions (set-2) Read More »
Q.1- A critical enzyme used directly in the synthesis of dTMP (thymidine) is a) Carbamoyl phosphate b) Aspartate Transcarbamylase c) Dihydrooratase d) Thymidylate synthase Q.2- In which phase of the cell cycle does DNA replication occur? a) G0 b) G1 c) S d) G2 Q.3-A 10-month-old baby boy presents with steatorrhea, recurrent pulmonary infections, GI
Molecular Biology- Multiple-choice questions (set-1) Read More »
Q.1- Glycogen phosphorylase, which mobilizes glycogen for energy, requires which of the following as a cofactor? a) Pyridoxal phosphate b)Tetra hydro folate c) Adenosyl Cobalamine d) Coenzyme A Q.2- Choose the incorrect statement about Active Site of an enzyme- a) The active site is a three-dimensional cleft b) The active site takes up a
Multiple Choice Questions- Enzymology Read More »
1) Which of the following is the best marker for the diagnosis of Acute pancreatitis? a) Lactase b) Amylase c) Cholesteryl esterase d) Υ- Glutamyl trans peptidase e) Sucrase 2) A gall stone that blocked the upper part of the bile duct would cause an – a) Increased formation of chylomicron b) Increased recycling of
Lipid Metabolism- Multiple choice questions- set-1 Read More »
