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Biosynthesis of cholesterol- a quick revision

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Biosynthesis of cholesterol The biosynthesis of cholesterol may be divided into five steps: (1) Synthesis of Mevalonate from acetyl-CoA. (2) Formation of Isoprenoid units from Mevalonate by loss of CO2. (3) Condensation of six isoprenoid units forms Squalene. (4) The cyclization of Squalene gives rise to the parent steroid, Lanosterol. (5)Formation of cholesterol from lanosterol.

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