USMLE styled question bank

Sanfilippo syndrome

Case details A 6-year-old boy is seen by a pediatrician because his parents are concerned about his aggressive behavior, hyperactivity, and a loss of language skills. He also has recently become increasingly unsteady on his feet and has experienced a recent seizure. Slight facial feature coarsening is noted. In which of the following processes is this child […]

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Digoxin- Chemistry and mechanism of action

A 57 -year-old man has been admitted with congestive heart failure. He has been given Digoxin, which helps the heart to beat more strongly and regularly. Digoxin is an ester that contains a sugar component (glycol) and a nonsugar (aglycone) component attached via oxygen. Digoxin should be best classified as a: A. Disaccharide B. Glycoprotein

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Gray Baby Syndrome and the Role of Glucuronic acid

Case details Infants have decreased ability to conjugate Glucuronic acid on to drugs such as Chloramphenicol. Administration of this antibiotic during the neonatal period can result in elevated plasma levels of the drug and a fetal shock-like syndrome referred to as Gray Baby syndrome. (Image courtesy-Gray Baby Syndrome: What You Need to Know) Glucuronic acid

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Chemical Nature of Sialic acid

The influenza virus infects cells by binding its viral hemagglutinin to “Sialic acid” on the surface of epithelial cells. Which of the following represents the true chemical nature of sialic acid? A. Glycolipid B. Amino sugar C. Amino sugar acid D. Lipoprotein E. Glycoprotein. Details The correct answer is C- Amino sugar acid. Sialic acid

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