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Glycolysis Review- NBME style questions with complete explanations

Q.1 Identify the Phosphoester that is predominantly encountered in erythrocytes and plays a vital role in modulating the oxygen-binding affinity of hemoglobin: A. 1,3-Bisphosphoglycerate B. 2,3-Bisphosphoglycerate C. Fructose 1,6-bisphosphate D. Fructose 6-phosphate E. Glucose 6-phosphate The correct answer is B. 2,3-Bisphosphoglycerate (2,3-BPG): 2,3-Bisphosphoglycerate is a negatively charged molecule found in high concentrations within erythrocytes. 2,3-BPG

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Biosynthesis of cholesterol- a quick revision

Biosynthesis of cholesterol The biosynthesis of cholesterol may be divided into five steps: (1) Synthesis of Mevalonate from acetyl-CoA. (2) Formation of Isoprenoid units from Mevalonate by loss of CO2. (3) Condensation of six isoprenoid units forms Squalene. (4) The cyclization of Squalene gives rise to the parent steroid, Lanosterol. (5)Formation of cholesterol from lanosterol.

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