Type of Inhibition Effect on Vmax and Km Reversible / Irreversible Examples Mnemonic Competitive (Inhibitor competes with substrate for the active site) Vmax: Unchanged Km: Increased Reversible 1) Statins – inhibit HMG-CoA Reductase (cholesterol-lowering) 2) PABA – inhibits Pteroyl Synthase (antibiotic) 3) Captopril – inhibits ACE (antihypertensive) 4) Oxamate – inhibits Lactate Dehydrogenase (poison) 5) […]
Q.1: Glycogen phosphorylase, which mobilizes glycogen for energy, requires which of the following as a cofactor? Adenosyl Cobalamine Coenzyme A Pyridoxal phosphate Tetrahydrofolate Thiamine pyrophosphate Correct Answer: C) Pyridoxal phosphate Explanation: Glycogen phosphorylase is instrumental in the process of glycogenolysis, where it facilitates the breakdown of glycogen into glucose-1-phosphate, thereby playing a vital role in
Enzymology Revision (Multiple Choice Questions With Complete Explanations) Read More »
A 54-year-old man complains of an acute onset of unilateral eye pain and a reduction in visual acuity. Conjunctival injection (eye redness) and a mild-dilated and non-reactive pupil are observed on physical examination. Fundoscopic examination reveals cupping of the optic disc. Recognizing the signs and symptoms of glaucoma, Acetazolamide is administered to decrease the production
