USMLE Content

Cholesterol-chemistry and metabolism- Multiple-choice questions

1)- Cholesterol is a precursor of all of the following except- a) Taurocholate b) Glycocholate c) Calcitriol d) Corticosteroids e) Calcitonin. 2)- All 27 carbon atoms of cholesterol are derived from- a) Acetyl CoA b) Acetoacetyl CoA c) Propionyl CoA d) Succinyl CoA e) Malonyl CoA 3)- Cytosolic  3-hydroxy-3-methylglutaryl CoA (HMG CoA) is reduced to […]

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Cholesterol metabolism- Multiple-choice questions

Q.1 – A gall stone that blocked the upper part of the bile duct would cause an increase in which of the following? a) The excretion of fats in the feces b) Formation of chylomicrons c) Excretion of bile salts d) Conjugation of bile acids e) Recycling of bile salts Q.2- An 8-year-old boy presents

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Chemistry of Nucleotides-Multiple-choice questions

1- Which statement best describes Xanthine ? a) It is a direct precursor of Guanine b) It covalently binds to Allopurinol c) It is oxidized to form Uric acid d) It is oxidized to form Hypoxanthine e) It is a substrate rather than a product of the enzyme Xanthine oxidase 2- Methylated heterocyclic bases of

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Multiple-choice questions- Chemistry of carbohydrates- Revision- Set-2

Q.1- Which of the following is not a disaccharide? a) Hyaluronic acid                                             b) Maltose c) Lactose                                            d) Sucrose                                                           Q.2- What is the molecular formula of Glucose? a) CH3OH                                             b) C12H22O11 c) C6H1206                                                             d)  C6H12O5                                            Q.3-Sucrose is composed of which two sugars? a) Glucose and Glucose                                 b) Glucose

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Biological oxidation and Electron transport chain (Multiple choice questions) – solved- part-3

Q.1- Choose a site along the electron transport chain out of the following that is not coupled to ATP synthesis: a) NADH- coenzyme Q (CoQ) reductase b) Succinate-Co Q reductase c) Cytochrome bc1 reductase d) Cytochrome oxidase e) None of the above. Q.2- Choose a statement out of the following that best describes the uncouplers

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Sanfilippo syndrome

Case details A 6-year-old boy is seen by a pediatrician because his parents are concerned about his aggressive behavior, hyperactivity, and a loss of language skills. He also has recently become increasingly unsteady on his feet and has experienced a recent seizure. Slight facial feature coarsening is noted. In which of the following processes is this child

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Gray Baby Syndrome and the Role of Glucuronic acid

Case details Infants have decreased ability to conjugate Glucuronic acid on to drugs such as Chloramphenicol. Administration of this antibiotic during the neonatal period can result in elevated plasma levels of the drug and a fetal shock-like syndrome referred to as Gray Baby syndrome. (Image courtesy-Gray Baby Syndrome: What You Need to Know) Glucuronic acid

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Chemical Nature of Sialic acid

The influenza virus infects cells by binding its viral hemagglutinin to “Sialic acid” on the surface of epithelial cells. Which of the following represents the true chemical nature of sialic acid? A. Glycolipid B. Amino sugar C. Amino sugar acid D. Lipoprotein E. Glycoprotein. Details The correct answer is C- Amino sugar acid. Sialic acid

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