1) – A mutation has changed an isoleucine residue of a protein to glutamic acid; which statement best describes its location in a hydrophilic exterior?
a) On the surface, since it is hydrophilic
b) Inside the core of the protein since it is hydrophobic
c) Anywhere inside or outside
d) Inside the core of protein since it has a polar but uncharged side chain
2) – Glycine and proline are the most abundant amino acids in the structure of- which of the following?
a) Hemoglobin
b) Myoglobin
c) Insulin
d) Collagen
3) – Some proteins contain additional amino acids that arise by modification of an amino acid already present in a peptide; examples include which of the following?
a) 4 -hydroxyproline
b) 5- hydroxylysine
c) Gamma Amino Butyric Acid
d) All of the above.
4) – Choose the incorrect statement out of the following:
a) Only L amino acids are found in the biological system
b) Glycine is optical inactive
c) Tyrosine is a modified amino acid
d) Seleno cysteine is the 21st amino acid
5) – Choose a nano peptide out of the following-
a) Oxytocin
b) Vasopressin
c) Bradykinin
d) All of the above.
6) – Which of the following amino acids carries a net positive charge at the physiological pH ?
a) Valine
b) Leucine
c) Isoleucine
d) None of the above
7) – Which of the following amino acids is a precursor for a mediator of allergies and inflammation?
a) Histidine
b) Tyrosine
c) Phenylalanine
d) Tryptophan
8) – The mother of a malnourished child has been instructed to include a complete protein in the diet for her child; which of the following proteins should be recommended?
a) Pulses
b) Wheat
c) Soy Protein
d) Milk
9) – All of the below-mentioned amino acids can participate in hydrogen bonding except one –
a) Serine
b) Cysteine
c) Threonine
d) Valine
10) – All of the following amino acids are both glucogenic as well as ketogenic except:
a) Isoleucine
b) Leucine
c) Tyrosine
d) Phenylalanine
11) – Which of the following amino acids is a precursor of niacin (Vitamin)?
a) Tyrosine
b) Threonine
c) Tryptophan
d) Phenylalanine
12) – The greatest buffering capacity at physiological pH would be provided by a protein-rich in which of the following amino acids?
a) Serine
b) Cysteine
c) Alanine
d) Histidine
13) – Which of the following peptides is cyclic-?
a) Glutathione
b) Gramicidin
c) Met encephalin
d) Leuencephalin
14) – Which of the following is not a fibrous protein?
a) Carbonic anhydrase
b) Collagen
c) Fibrinogen
d) Keratin
15)-Which of the following amino acids is a limiting amino acid in pulses?
a) Leucine
b) Lysine
c) Methionine
d) Glutamine
16)- Which of the following is not a hemoprotein?
a) Catalase
b) Myeloperoxidase
c) Glutathione peroxidase
d) Aconitase
17) – All the below-mentioned proteins are metalloproteins except-
a) Carbonic anhydrase
b) Xanthine oxidase
c) Lactate dehydrogenase
d) Superoxide dismutase
18) – Which of the following is a peptide antibiotic?
a) Erythromycin
b) Gramicidin
c) Ciprofloxacin
d) Tetracycline
19) – Choose the Anticancer peptide out of the following-
a) Bleomycin
b) Methotrexate
c) Cytosine Arabinoside
d) Dideoxyinosine
20) – Which of the following amino acids is most compatible with an α-helical structure?
a) Tryptophan
b) Alanine
c) Leucine
d) Proline
21) – Which of the following can be found with the highest concentration of cystine?
a) Melanin
b) Keratin
c) Collagen
d) Myosin
22) – In scurvy, which amino acid that is usually part of collagen is not synthesized?
a) Hydroxy-tryptophan
b) Hydroxy-tyrosine
c) Hydroxy-alanine
d) Hydroxy-proline
23) – A child with tall stature, loose joints, and detached retinas is found to have a mutation in collagen. Which of the following amino acids is the recurring amino acid most likely to be altered in mutations that distort collagen molecules?
a) Glycine
b) Tyrosine
c) Tryptophan
d) Tyrosine
24) – Which one of the following amino acids may be considered a hydrophobic amino acid at physiological p H of 7.4?
a) Isoleucine
b) Arginine
c) Aspartic acid
d) Threonine
25) – Which of the characteristics below apply to the amino acid Glycine?
a) Optically inactive
b) Hydrophilic, basic, and charged
c) Hydrophobic
d) Hydrophilic, acidic, and charged
26) – Which of the following amino acids in myoglobin, a globular protein, is highly likely to be localized within the interior of the molecule?
a) Arginine
b) Valine
c) Aspartic acid
d) Lysine
27) – Which of the amino acids below is the uncharged derivative of an acidic amino acid?
a) Cystine
b) Tyrosine
c) Glutamine
d) Serine
28) – Choose the correct category for milk protein casein out of the following-
a) Nucleoprotein
b) Phosphoprotein
c) Lipoprotein
d) Glycoprotein
Answers-
1- a
2- d
3- d
4- c
5- d
6- d
7- a
8- d
9- d
10- b
11- c
12- d
13- b
14- a
15- c
16- d
17- c
18- b
19- a
20- b
21- b
22- d
23- a
24- a
25- a
26- b
27- c
28- b
